He was pictured on a wheelchair as he prepared to board a flight to Rio de Janeiro - and Brazil doctor Rodrigo Lasmar confirmed: "He will be out for around two-and-a-half and three months".
Images of Sunday's unfortunate tackle on Neymar by Marseille's player Bouna Sarr were being shown repeatedly on TV, often in slow motion, before he was stretchered off.
His absence from the Madrid match on Tuesday is a huge blow with PSG attempting to overhaul a 3-1 first-leg defeat at the Bernabeu.
At the Mater Dei de Belo Horizonte hospital, an entire wing has been reserved for Neymar and his entourage, and staff have been warned to uphold the facility's policy regarding confidentiality, said GloboEsporte.
Paris Saint-Germain reached the semi-finals of the French Cup and stayed on course for their title defence with a 3-0 trouncing of bitter rivals Olympique de Marseille on Wednesday. We are a family and he is a gentleman.
Neymar is sure to miss the rematch of the Champions League's eighth rounds against Real Madrid on March 6th, although Parisian coach Unai Emery hoped he would get involved. They have already gone to Brazil.
Brazilians care little about the impact on PSG.
'We do not have the right time, but it will certainly be that day. "But there is a noticeable haste to find a solution so that Neymar will have recovered in time", an ESPN Brasil sports commentator, Mauro Cezar Pereira, told AFP.